Jaladhar Mahato, PhD
Postdoctoral Research Scientist
Department of Chemistry ∣∣ Columbia University
Havemeyer 611; 3000 Broadway; New York, NY 10027
E-mail: j.mahato@columbia.edu
Expertise: Fluorescence microscopy | single-molecule imaging | glassy dynamics
Focus: Disordered dynamics in soft matter
Open to: collaboration / talks / research exchange
‣ 2023–Present
Postdoctoral Research Scientist: Columbia University, New York, USA
‣ 2021–2023
Roy J Carver Postdoctoral Fellow: Iowa State University, Ames, IA, USA
‣ 2014–2021
Ph.D. in Chemistry: Indian Institute of Technology Bombay, Mumbai, MH, India
‣ 2012–2014
MSc. in Chemistry: Indian Institute of Technology Bombay, Mumbai, MH, India
‣ 2009–2012
BSc. in Chemistry: Jagannath Kishore College-The University of Burdwan, Purulia, WB, India
Postdoctoral Research Scientist
Department of Chemistry, Columbia University
Advisor: Ruben L Gonzalez Jr
Research Highlights
✦ Investigating the biophysical role of RF3 dynamics during RF2- and tRNA-mediated quality control in gene expression
Postdoctoral Research Scientist
Department of Chemistry, Columbia University
Advisor: Prof. Laura J. Kaufman
Research Highlights
✦ Investigated glassy dynamics using SM rotational and translational measurements.
✦ Simulated the Generalized Langevin Equation (GLE) to validate and interpret SM results.
✦ Developed SM defocused imaging using new internal reflection (TIR) excitation for 3D molecular orientation retrieval.
✦ Designed a strategy to construct susceptibility spectra from SM rotational fluctuation.
Roy J Carver Bioscience Innovation Postdoctoral Fellow
Department of Chemistry, Iowa State University
Advisor: Prof. Jacob W. Petrich
Research Highlights
✦ Investigated nanostructures in ionic liquids using confocal FCS with time-correlated single-photon counting (TCSPC).
Ph.D. in Chemistry
Department of Chemistry, Indian Institute of Technology Bombay
Advisor: Prof. Arindam Chowdhury
Dissertation Title: Probing Molecular Interactions and Orientations Using Spectrally and Polarization Resolved Fluorescence Microscopy
Research Highlights
✦ Developed a method to decipher genuine pauses within a super-resolved trajectory using polarization-resolved SM tracking (PR-SMT).
✦ Designed spectrally-resolved sensitized emission imaging to probe biomolecular interaction in noncovalent assemblies.
✦ Developed a polarization-resolved helical anisotropy imaging method to investigate polymorphism in amyloid fibrils.
✦ Designed and assembled a custom super-resolution (dSTORM) microscope for imaging peptide–based amyloid fibrils.
✦ Characterized self-assembled selenopeptides organized into different supra-molecular architecture.
MSc. Dissertation
Department of Chemistry, Indian Institute of Technology Bombay
Advisor: Prof. Arindam Chowdhury
Dissertation Title: Understanding Relation between Jump-Distribution and Mean Squared Displacement of Single-Molecule Tracers
Research Highlights
✦ Simulation of "Anomalous yet Brownian" transport processes using MATLAB.